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Image Search Results
Journal: Scientific Reports
Article Title: Association of attenuated leptin signaling pathways with impaired cardiac function under prolonged high-altitude hypoxia
doi: 10.1038/s41598-024-59559-6
Figure Lengend Snippet: Hypoxia induced PVH, RVH, and impaired left ventricular contraction and relaxation in rats. ( A ) Representative images of transthoracic echocardiography in normoxic and hypoxic rats to quantify the indicators from ( B – M ). ( B ) Indicators of pulmonary artery hemodynamics. ( C ) Indicators of right ventricular function assessment. ( D ) Tricuspid annular plane systolic excursion (TAPSE). ( E ) Right ventricular cardiac output (CO) and cardiac index (CI). ( F ) Coronary flow reserve (CFR). ( G ) Indicators of left ventricular diastolic function, including left ventricular isovolumic relaxation time (IVRT), isovolumic contraction time (IVCT), aortic ejection time (AET). ( H ) Early diastolic mitral annular velocity (e'), ratio of mitral valve early diastolic velocity (MV E) to mitral valve atrial contraction velocity (MV A), E/e', and the ratio of e' to late diastolic mitral annular velocity (e'/a'). ( I ) Left ventricular anterior wall thickness at end-diastole (LVAW, d) and at end-systole (LVAW,s) , left ventricular volume at end-diastole (LV Volume, d), and left ventricular volume at end- systole (LV Volume, s). ( J ) LV mass. ( K ) Left ventricular ejection fraction (EF) and fractional shortening (FS). ( L ) Left ventricular global longitudinal strain (GLS). ( M ) Quantification of radial strain (RS), radial strain rate (RSR), longitudinal strain (LS), longitudinal strain rate (LSR). n = 7–9. Results are presented as mean ± SEM. The p values are shown on the top of compared group by unpaired t-test.
Article Snippet: Lung function, cardiovascular function, electrocardiogram, body composition, and microvascular oxygen saturation were examined by a digital spirometer (MasterScope ® , Jaeger, Germany),
Techniques: